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Sinusitis Patient’s Guide — References

This page lists the academic and web-based sources that informed the Sinusitis Patient’s Guide. It is provided for those who wish to review the references used within the guide.

Web Resources:

Academic References:

  • Elam, T., Raiculescu, S., Biswal, S., Zhang, Z., Orestes, M., & Ramanathan, M. (2023) ‘Air Pollution Exposure and the Development of Chronic Rhinosinusitis in the Active Duty Population’, Military Medicine, 188(7–8), pp. e1965–e1969. Available at: https://academic.oup.com/milmed/article/188/7-8/e1965/6499880 (Accessed: 17 January 2025).
  • Chegini, Z., Noei, M., Hemmati, J., Arabestani, M.R. and Shariati, A. (2023) 'The destruction of mucosal barriers, epithelial remodeling, and impaired mucociliary clearance: possible pathogenic mechanisms of Pseudomonas aeruginosa and Staphylococcus aureus in chronic rhinosinusitis', Cell Communication and Signaling, 21(306). Available at: https://biosignaling.biomedcentral.com/articles/10.1186/s12964-023-01347-2 (Accessed: 17 January 2025).
  • Eshaghi Ghalibaf, M.H., Kianian, F., Beigoli, S., Behrouz, S., Marefati, N., Boskabady, M., & Boskabady, M.H. (2023) 'The effects of vitamin C on respiratory, allergic and immunological diseases: an experimental and clinical-based review', Inflammopharmacology, 31, pp. 653–672. Available at: https://link.springer.com/article/10.1007/s10787-023-01169-1 (Accessed: 17 January 2025).
  • Hemilä, H. & Chalker, E. (2013) 'Vitamin C for preventing and treating the common cold', Cochrane Database of Systematic Reviews, (1), CD000980. Available at: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD000980.pub4/full (Accessed: 17 January 2025).
  • Poudineh, M., Nikzad, F., Parvin, S., Ghaheri, M., Sabbaghi, S., Kazemi, E., Ghodrati, M.M., Mohammadyari, F., Saeedpour, S., Mohammadpour, S., Gohari, N.S.F., Heydarasadi, F., Abolhasani, D., Olangian-Tehrani, S., & Alinezhad, A. (2021) 'Therapeutic Effects of Vitamins and Nutritional Supplements on Chronic Sinusitis: A Systematic Review', Nutrition and Metabolic Insights, 14, pp. 1–10. Available at: https://journals.sagepub.com/doi/10.1177/11786388241263680 (Accessed: 17 January 2025).
  • Baruah, B., Gupta, A., Kumar, A., & Kumar, A. (2020) 'The role of oral vitamin D3 supplementation in the treatment of Chronic Rhinosinusitis in adults with Vitamin D deficiency', Journal of Family Medicine and Primary Care, 9(6), pp. 2877–2879. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC7491765/ (Accessed: 17 January 2025).
  • Braun, J.M., Schneider, B., & Beuth, H.J. (2005) 'Therapeutic use, efficiency and safety of the proteolytic pineapple enzyme Bromelain-POS in children with acute sinusitis in Germany', In Vivo, 19(2), pp. 417–421. Available at: https://pubmed.ncbi.nlm.nih.gov/15796206/ (Accessed: 17 January 2025).
  • Passali, D., Passali, G.C., Bellussi, L.M., Sarafoleanu, C., Loglisci, M., Manea, C., Iosif, C., & Passali, F.M. (2018) 'Bromelain’s penetration into the blood and sinonasal mucosa in patients with chronic rhinosinusitis', Acta Otorhinolaryngologica Italica, 38(3), pp. 225–228. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC6036946/ (Accessed: 17 January 2025).
  • Tiboc-Schnell, C.N., Filip, G.A., Man, S.C., Decea, N., Moldovan, R., Opris, R., Sas, V., & Tabaran, F. (2020) 'Quercetin attenuates naso-sinusal inflammation and inflammatory response in lungs and brain on an experimental model of acute rhinosinusitis in rats', Journal of Physiology and Pharmacology, 71(4). Available at: https://pubmed.ncbi.nlm.nih.gov/33214336/ (Accessed: 17 January 2025).
  • Otaki, A., Furuta, A., and Asano, K. (2023) 'Quercetin-Induced Enhancement of Nasal Epithelial Cells’ Ability to Produce Clara Cell 10-kD Protein In Vitro and In Vivo', Medicines, 10(4), p. 28. Available at: https://www.mdpi.com/2305-6320/10/4/28 (Accessed: 17 January 2025).
  • Bahtouee, M., Monavarsadegh, G., Ahmadipour, M., Motieilangroodi, M., Motamed, N., Saberifard, J., Eghbali, S., Adibi, H., Maneshi, H., & Malekizadeh, H. (2017) 'Acetylcysteine in the treatment of subacute sinusitis: A double-blind placebo-controlled clinical trial', Ear, Nose & Throat Journal, 96(1), pp. E7–E11. Available at: https://pubmed.ncbi.nlm.nih.gov/28122105/ (Accessed: 17 January 2025).
  • Wee, J.H., Park, J.H., Park, M.W., Choi, Y.S., & Jung, H.J. (2024) 'Sinus Irrigation with N-Acetylcysteine after Endoscopic Sinus Surgery for Chronic Rhinosinusitis: A Preliminary Report of a Single-Blind Randomized Controlled Trial', Diagnostics, 14(15), p. 1678. Available at: https://pubmed.ncbi.nlm.nih.gov/39125554/ (Accessed: 17 January 2025).
  • Hemilä, H. (2011) 'Zinc lozenges may shorten the duration of colds: a systematic review', Open Respiratory Medicine Journal, 5, pp. 51–58. Available at: https://pubmed.ncbi.nlm.nih.gov/21769305/ (Accessed: 17 January 2025).
  • Akbari Dilmaghani, N., Alani, N., & Fazeli, S. (2019) 'A Randomized Clinical Trial of Elemental Zinc Add-on Therapy on Clinical Outcomes of Patients with Chronic Rhinosinusitis with Nasal Polyposis (CRSwNP)', Iranian Journal of Pharmaceutical Research, 18(3), pp. 1595–1601. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC6934942/ (Accessed: 17 January 2025).
  • Bianco, M.R., Ralli, M., Modica, D.M., Amata, M., Poma, S., Mattina, G., & Allegra, E. (2021) 'The Role of Probiotics in Chronic Rhinosinusitis Treatment: An Update of the Current Literature', Healthcare, 9(12), p. 1715. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC8701913/ (Accessed: 17 January 2025).
  • Standyło, A., Obuchowska, A., Horaczyńska-Wojtaś, A., & Mielnik-Niedzielska, G. (2024) 'Effects of Probiotic Supplementation during Chronic Rhinosinusitis on the Microbiome', Journal of Clinical Medicine, 13(6), p. 1726. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC10971434/ (Accessed: 17 January 2025).
  • Attia, T.M. (2019) 'Role of Omega-3 Polyunsaturated Fatty Acids in Treatment of Nasal Polyposis', American Journal of Rhinology & Allergy, 34(1). Available at: https://doi.org/10.1177/1945892419871802 (Accessed: 17 January 2025).
  • Sawane, K., Nagatake, T., Hosomi, K., Hirata, S., Adachi, J., Abe, Y., Isoyama, J., Suzuki, H., Matsunaga, A., Fukumitsu, S., Aida, K., Tomonaga, T., Arita, M., & Kunisawa, J. (2019) 'Dietary Omega-3 Fatty Acid Dampens Allergic Rhinitis via Eosinophilic Production of the Anti-Allergic Lipid Mediator 15-Hydroxyeicosapentaenoic Acid in Mice', Nutrients, 11(12), p. 2868. Available at: https://www.mdpi.com/2072-6643/11/12/2868 (Accessed: 17 January 2025).
  • Birdane, L., Cingi, C., Muluk, N.B., San, T., & Burukoglu, D. (2016) 'Evaluation of the efficacy of curcumin in experimentally induced acute sinusitis in rats', Ear, Nose & Throat Journal, 95(12), pp. E21–E27. Available at: https://pubmed.ncbi.nlm.nih.gov/27929603/ (Accessed: 17 January 2025).
  • Wu, S. and Xiao, D. (2016) 'Effect of curcumin on nasal symptoms and airflow in patients with perennial allergic rhinitis', Annals of Allergy, Asthma & Immunology, 117(6), pp. 697–702.e1. Available at: https://pubmed.ncbi.nlm.nih.gov/27789120/ (Accessed: 17 January 2025).
  • Mahmoodpoor, A., Faramarzi, E., Reyhanifard, A., Shamekh, A., Nikanfar, S., Azizi-Zeinalhajlou, A., and Sanaie, S. (2022) 'The effects of selenium supplementation on inflammatory markers in critically ill patients', SN Applied Sciences, 4(1), p. 326. Available at: https://link.springer.com/article/10.1007/s42452-022-05208-4 (Accessed: 17 January 2025).
  • Nikakhlagh, S., Ramezani, Z., and Kiani, A. 'Comparison of tissue level of selenium and zinc in patients with nasal polyposis and healthy people', Clinical Epidemiology and Global Health, 8(4), pp. 1291–1295. Available at: https://doi.org/10.1016/j.cegh.2020.07.005 (Accessed: 17 January 2025).
  • Guven, M., Aladag, I., Eyibilen, A., Filiz, N.O., Ozyurt, H., and Yelken, K. (2007) 'Experimentally induced acute sinusitis and efficacy of vitamin A', Acta Otolaryngologica, 127(8), pp. 855–860. Available at: https://pubmed.ncbi.nlm.nih.gov/17762998/ (Accessed: 17 January 2025).
  • Ünal, M., Öztürk, C., Aslan, G., Aydin, Ö., and Görür, K. (2002) 'The effect of high single dose parenteral vitamin A in addition to antibiotic therapy on healing of maxillary sinusitis in experimental acute sinusitis', International Journal of Pediatric Otorhinolaryngology, 64(2), pp. 93–100. Available at: https://doi.org/10.1016/S0165-5876(02)00175-1 (Accessed: 17 January 2025).
  • Johnson, S. (2001) 'The multifaceted and widespread pathology of magnesium deficiency', Medical Hypotheses, 56(2), pp. 163–170. Available at: https://pubmed.ncbi.nlm.nih.gov/11425281/ (Accessed: 17 January 2025).
  • Önerci, M. and Kuş, S. (1995) 'Trace elements in chronic sinusitis', European Archives of Oto-Rhino-Laryngology, 252(6), pp. 374–375. Available at: https://pubmed.ncbi.nlm.nih.gov/8679159/ (Accessed: 17 January 2025).
  • Shahid, M., Naureen, I., Riaz, M., Anjum, F., Fatima, H., and Rafiq, M.A. (2021) 'Biofilm Inhibition and Antibacterial Potential of Different Varieties of Garlic (Allium sativum) Against Sinusitis Isolates', Dose-Response, 19(4), pp. 1–10. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC8532223/ (Accessed: 17 January 2025).
  • Kyo, E., Uda, N., Kasuga, S., and Itakura, Y. (2001) 'Immunomodulatory effects of aged garlic extract', Journal of Nutrition, 131(3s), pp. 1075S–1079S. Available at: https://pubmed.ncbi.nlm.nih.gov/11238820/ (Accessed: 17 January 2025).
  • Feazel, L. M., Robertson, C. E., Ramakrishnan, V. R., and Frank, D. N. (2012) 'Microbiome complexity and Staphylococcus aureus in chronic rhinosinusitis', The Laryngoscope, 122(2), pp. 467–472. Available at: https://pubmed.ncbi.nlm.nih.gov/22253013/ (Accessed: 16 January 2025).
  • Gómez-García, M., Moreno-Jimenez, E., Morgado, N., García-Sánchez, A., Gil-Melcón, M., Pérez-Pazos, J., Estravís, M., Isidoro-García, M., Dávila, I., and Sanz, C. (2021) 'The Role of the Gut and Airway Microbiota in Chronic Rhinosinusitis with Nasal Polyps: A Systematic Review', International Journal of Molecular Sciences, 25(15), 8223. Available at: https://www.mdpi.com/1422-0067/25/15/8223/ (Accessed: 16 January 2025).
  • Abreu, N. A., Nagalingam, N. A., Song, Y., Roediger, F. C., Pletcher, S. D., Goldberg, A. N., and Lynch, S. V. (2012) 'Sinus microbiome diversity depletion and Corynebacterium tuberculostearicum enrichment mediates rhinosinusitis', Science Translational Medicine, 4(151), p. 151ra124. Available at: https://pubmed.ncbi.nlm.nih.gov/22972842/ (Accessed: 16 January 2025).
  • Shi, N., Li, N., Duan, X., and Niu, H. (2017) 'Interaction between the gut microbiome and mucosal immune system', Military Medical Research, 3, 14. Available at: https://mmrjournal.biomedcentral.com/articles/10.1186/s40779-017-0122-9 (Accessed: 16 January 2025).
  • Cervin, A. U. (2017) 'The potential for topical probiotic treatment of chronic rhinosinusitis, a personal perspective', Frontiers in Cellular and Infection Microbiology, 7, 530. Available at: https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2017.00530/full (Accessed: 16 January 2025).
  • Szaleniec, J., Gibała, A., Pobiega, M., Parasion, S., Składzień, J., Stręk, P., Gosiewski, T., and Szaleniec, M. (2019) 'Exacerbations of Chronic Rhinosinusitis—Microbiology and Perspectives of Phage Therapy', Antibiotics, 8(4), 175. Available at: https://www.mdpi.com/2079-6382/8/4/175 (Accessed: 16 January 2025).
  • Gulliver, E. L., Young, R. B., Chonwerawong, M., D'Adamo, G. L., Thomason, T., Widdop, J. T., Rutten, E. L., Marcelino, V. R., Bryant, R. V., Costello, S. P., O'Brien, C. L., Hold, G. L., Giles, E. M., and Forster, S. C. (2021) 'The future of microbiome‐based therapeutics', Frontiers in Cellular and Infection Microbiology, 11, 669041. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC9322325/ (Accessed: 16 January 2025).
  • Zheng, D., Liwinski, T., and Elinav, E. (2020) 'Interaction between microbiota and immunity in health and disease', Nature Reviews Immunology, 20(9), pp. 495–506. Available at: https://www.nature.com/articles/s41422-020-0332-7 (Accessed: 16 January 2025).
  • Sorbara, M. T., and Pamer, E. G. (2021) 'Microbiome-based therapeutics', Nature Reviews Microbiology, 19(5), pp. 305–323. Available at: https://www.nature.com/articles/s41579-021-00667-9 (Accessed: 16 January 2025).